Senior Data Scientist #4887 at GRAIL
Menlo Park, CA
$156,000–$187,000from the description
Jul 6, 2026
Menlo Park, CA
Jul 21, 2026
What this job asks for AI summary
A senior data science role on the Computational Biology team, focused on analyzing large-scale genomic datasets from a commercial multi-cancer early detection product and related clinical studies. The work centers on building predictive models that monitor and maintain classifier performance over time, integrating DNA methylation, cancer biology, epidemiology, and statistical methods. The role suits a computationally strong researcher with NGS and omics experience who is comfortable working across machine learning, clinical, and laboratory teams.
Senior level · 2+ years · San Jose-Sunnyvale-Santa Clara, CA · Doctorate required · Full-time
“or” means any one of them counts — you don't need all of them.
Posted 2 times — it's one opening, so apply once.
We read this from the posting text with AI. Skim the description below before ruling yourself out.
How this req sits in the market our data
Roughly 870 people in the San Jose-Sunnyvale-Santa Clara, CA area plausibly meet what this posting asks for (data scientists). range 370–1,300
Applicant volume Heavy — This req sits in a large pool with little in its requirements to thin it, and auto-apply tools fire at everything in the occupation. Applying early and leading with the rare skills below is what gets read.
Most people in this occupation already list these. Still required — just not what gets you shortlisted.
What the occupation pays Median $189,150 (middle half $152,859–$224,286). This posting is about at that midpoint.
Estimated from BLS employment for this occupation and area, per-skill prevalence across our listing corpus, and published wage benchmarks — as of Jul 28, 2026. It is a model, not a headcount.
Why we read it this way (5)
The role is based in Menlo Park, CA (moving to Sunnyvale, CA in Fall 2026); the CBSA reported reflects the broader San Jose-Sunnyvale-Santa Clara metro that encompasses both cities. The role is not fully remote — a minimum of 40% on-site presence is required.
The JD lists R as 'preferred' within the required qualifications section ('R (preferred) or Python'), meaning either language satisfies the hard gate on large-scale omics data work. R is emitted as the primary skill with Python as an alternative; Python is also separately listed under Preferred Qualifications with additional tooling context.
A Ph.D. is explicitly required ('Ph.D. in Bioinformatics, Data Science, Computational Biology…'), making Doctorate the minimum degree. The 2+ years of relevant experience is stated as a post-PhD requirement.
Cancer epigenetics/biology, tumor genetics, and modern AI techniques appear only under 'Preferred Qualifications' and are not emitted as hard gates.
The alternative occupation code 15-1299 is noted as a distant runner-up given the computational biology framing, but 15-2051 (Data Scientists) is clearly the best fit given the ML modeling, statistical analysis, and data science workflow emphasis.
Read the full posting
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