South San Francisco, CA

Salary
$175,000–$210,000
Posted
Jul 6, 2026
Location
South San Francisco, CA
Last confirmed open
Jul 21, 2026

What this job asks for AI summary

A senior software engineering role focused on building low-latency, high-performance software to control custom DNA synthesis and gene sequencing instrumentation. The work spans firmware, real-time operating systems, hardware bring-up, and integration with back-end web services and bioinformatics pipelines. Suited to an experienced engineer comfortable working across C, C++, or Rust at the intersection of hardware and software in a startup environment.

Senior level · 10+ years · National · Bachelor's required · Full-time

Advertised as Staff, but the requirements read as Senior.

Must have (5)
C++, C or RustTypeScript or PythonRTOShigh-speed buses (SPI, Ethernet, USB)Git
Nice to have (7)
ReactFPGAAWS, Azure or GCPC#.NETWPFimage processing

“or” means any one of them counts — you don't need all of them.

We read this from the posting text with AI. Skim the description below before ruling yourself out.

How this req sits in the market our data

What gives you an edge
RTOS6%Rust13%

Rare in this occupation — lead with these, and say what you built with them.

What won't set you apart
TypeScript51%

Most people in this occupation already list these. Still required — just not what gets you shortlisted.

What the occupation pays Median $138,970 (middle half $107,524–$175,762).

Estimated from BLS employment for this occupation and area, per-skill prevalence across our listing corpus, and published wage benchmarks — as of Jul 28, 2026. It is a model, not a headcount.

Why we read it this way (6)

The title is 'Senior Staff Instrument Software Engineer' but the actual requirements — 10+ years of experience, significant Staff-level or equivalent senior technical leadership — are consistent with a Senior engineer band. The 'Staff' label in the title is treated as the advertised level; the scope and requirements do not clearly demonstrate org-wide, cross-team technical authority beyond a single product area, so the role is sized at Senior.

The posting has two overlapping requirements sections (an early bullet list and a later 'Required Skills' block). The later 'Required Skills' block is treated as authoritative for hard gates; the earlier bullets are largely duplicated there. C# appears only in the early bullet list and is not repeated in 'Required Skills', so it is marked preferred.

The degree requirement is ambiguous: the early section says 'BS in Computer Science or related field' (hard gate language), while 'Desired Skills' lists 'Bachelor's or master's degree' and 'Preferred qualifications' lists 'Master's or PhD'. The minimum hard-required degree is treated as a Bachelor's based on the early requirements block.

The skills 'memory management', 'firmware development', and 'high-speed buses (SPI, Ethernet, USB)' are named as required capabilities rather than discrete tool names, but they represent concrete, testable technical competencies explicitly gated in the Required Skills section and are retained for that reason.

No compensation figures are provided.

Ignored 2 non-technology phrase(s) as skills (responsibilities/concepts, not named tools): memory management, firmware development.

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